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Felix 2D/ND
Programs for processing, displaying, and
analyzing all types of high-resolution,
solid-state, in vivo, one- to
four-dimensional, and homonuclear and
heteronuclear data using the same set of
processing tools.
Learn more... |
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Felix Assign
A unique package for computer-assisted
assignment of 2D, 3D, and 4D NMR spectra of
proteins and nucleic acids, which includes
tools for semiautomatic spin system
detection, identification, sequential
assignment, and NOE crosspeak assignment.
Learn more... |
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Felix Autoscreen
Automates the processing and management of
large sets of NMR data.
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Felix Model
Provides direct interaction between
experimental NOESY data, molecular
structures, and back-calculated NOESY data
within an integrated interface.
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Felix Analytical
Designed to provide semi-automated analysis
and assignment of two dimensional spectra of
organic molecules. |
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(Click image for larger view) |
The spin systems and
sequential assignments of human hnRNP C
RNA-binding domain10 were automatically
assigned using Felix Assign and the 3D HNCACB and CBCA(CO)NH spectra. The
HNi-Ni-Cαi and HNi-Ni-Cαi-1 correlations
(blue peaks) and the HNi-Ni-Cβi and
HNi-Ni-Cβi-1 correlations (green peaks) are
depicted along with the sequential walk
(yellow) within strip plots of the 3D HNCACB
spectrum centered at the Ni planes and the
HNi vertical positions. |
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(Click image for larger view) |
Expanded regions of the
experimental (top) and simulated (bottom) 2D
NOESY spectra of Zinc Rubredoxin are shown.
The simulated NOE intensities were generated
from the minimized X-ray structure 3 using
the matrix doubling11 methodology within NMR
Refine and the simulated spectra was
generated and displayed as a stack plot
within Felix Model. |
